| Date | Location | Result | |
| Dec 11, 2021 | Fargo, ND | North Dakota State 27, ETSU 3 | Box score |
| Dec 04, 2021 | Johnson City, Tenn. | ETSU 32, Kennesaw State 31 | Box score |
| Nov 20, 2021 | Johnson City, Tenn | ETSU 38, Mercer 35 | Box score |
| Nov 13, 2021 | Cullowhee, N.C. | ETSU 56, Western Caro. 35 | Box score |
| Nov 06, 2021 | Johnson City, Tenn. | ETSU 27, VMI 20 | Box score |
| Oct 23, 2021 | Greenville, S.C. | ETSU 17, Furman 13 | Box score |
| Oct 16, 2021 | Chattanooga, Tenness | Chattanooga 21, ETSU 16 | Box score |
| Oct 09, 2021 | Johnson City, Tenn. | ETSU 48, The Citadel 21 | Box score |
| Oct 02, 2021 | Johnson City, Tenn. | ETSU 27, Wofford 21 | Box score |
| Sep 25, 2021 | Birmingham, Ala. | ETSU 55, Samford 48 | Box score |
| Sep 18, 2021 | Johnson City, Tenn. | ETSU 38, Delaware State 6 | Box score |
| Sep 11, 2021 | Johnson City, Tenn. | ETSU 45, UVA Wise 14 | Box score |
| Sep 04, 2021 | Nashville, | ETSU 23, Vanderbilt 3 | Box score |