| Date | Results | |
| Apr 23, 2022 | Furman 4, East Tennessee State 2 | |
| Apr 22, 2022 | East Tennessee State 4, Samford 0 | |
| Apr 21, 2022 | East Tennessee State 4, UNC Greensboro 0 | |
| Apr 16, 2022 | Furman 5, East Tennessee State 2 | |
| Apr 08, 2022 | ETSU 7, UNC Greensboro 0 | |
| Apr 03, 2022 | East Tennessee State 6, Samford Women's Tennis 1 | |
| Apr 01, 2022 | East Tennessee State 4, Charlotte 3 | |
| Mar 26, 2022 | East Tennessee State 6, Chattanooga 1 | |
| Mar 24, 2022 | East Tennessee State 6, Mercer Women's Tennis 1 | |
| Mar 17, 2022 | FIU 5, East Tennessee State 2 | |
| Mar 16, 2022 | East Tennessee State 7, Northern Iowa Women's Tennis 0 | |
| Mar 16, 2022 | East Tennessee State 4, Harvard Women's Tenis 0 | |
| Mar 11, 2022 | East Tennessee State 7, Wofford 0 | |
| Mar 08, 2022 | East Tennessee State 4, Lipscomb Women 0 | |
| Feb 27, 2022 | East Tennessee State 6, Miami University 1 | |
| Feb 25, 2022 | East Tennessee State 4, Xavier 3 | |
| Feb 19, 2022 | East Tennessee State 7, App State 0 | |
| Feb 18, 2022 | East Tennessee State 7, Western Carolina University 0 | |
| Feb 12, 2022 | VCU 4, East Tennessee State 0 | |
| Feb 04, 2022 | Vanderbilt 5, East Tennessee State 2 | |
| Jan 30, 2022 | East Tennessee State 7, Belmont 0 | |
| Jan 28, 2022 | East Tennessee State 7, Middle Tennessee W 0 | |
| Jan 23, 2022 | NC State Wolfpack 6, East Tennessee State 1 | |
| Jan 22, 2022 | Virginia Tech Women's Tennis 6, East Tennessee State 1 | |
| Jan 14, 2022 | Kentucky 4, East Tennessee State 3 | |
| Jan 14, 2022 | Kentucky 4, East Tennessee State 3 | |